Scientifically Backed Benefits for Skin, Joints, and Bones: COLLAGEN+ BY COSMOPHARM®

Collagen is a structural protein responsible for keeping our skin firm, our joints flexible, and our bones strong. It represents nearly 30% of the total protein content in the human body and plays a vital role in the integrity of connective tissues. However, as we age, the body’s natural collagen production begins to decline—by about 1% per year after the age of 25. This gradual reduction contributes to wrinkles, sagging skin, stiff joints, weaker bones, and reduced muscle mass.

Collagen 500+ by Cosmo Pharm® is a powerful formula designed to help combat this age-related decline. Enriched with Fortigel® hydrolyzed collagen peptides, vitamin C, zinc, and vitamin E, it offers targeted nutritional support for anyone looking to improve their skin health, joint function, bone strength, and overall well-being.

What Is Collagen 500+ and Why Is It Unique?

Cosmo Pharm®’s Collagen 500+ stands apart from generic collagen supplements because of its use of Fortigel®, a clinically studied, bioavailable form of bovine collagen peptides. Unlike standard gelatin or unhydrolyzed collagen, Fortigel® is broken down into peptides that are readily absorbed and transported to target tissues.

Its supporting ingredients—vitamin C, zinc, and vitamin E—were specifically chosen to enhance collagen synthesis, protect cells from oxidative damage, and support the structure of skin, bones, and joints. Let’s explore how each component contributes to the supplement’s effectiveness.

Composition of COLLAGEN+

1. Fortigel® Hydrolyzed Collagen Peptides
   Fortigel® is a proprietary form of collagen peptides derived from bovine sources. It contains bioactive peptides that specifically stimulate chondrocytes—the cells responsible for maintaining healthy cartilage.
   Benefits:

• Stimulates cartilage regeneration
• Improves joint mobility and reduces pain
• Enhances skin firmness and elasticity
• Supports bone metabolism
  Scientific Source:
  A 24-week double-blind, placebo-controlled study found that Fortigel® significantly improved joint pain in athletes.
  https://pubmed.ncbi.nlm.nih.gov/18416885/

2. Vitamin C (Ascorbic Acid)
   Vitamin C is essential for the biosynthesis of collagen. It acts as a co-factor for enzymes involved in the stabilization and cross-linking of the collagen molecule, and it’s also a powerful antioxidant that neutralizes free radicals.
   Benefits:

• Boosts natural collagen production
• Protects skin from oxidative stress and UV damage
• Supports immune function and wound healing

3. Zinc
   Zinc plays a structural and catalytic role in over 300 enzymes and is especially important for skin integrity, immune defense, and wound healing.
   Benefits:

• Accelerates skin healing
• Regulates inflammation
• Reduces acne and improves skin clarity
• Supports bone density

4. Vitamin E (Tocopherol)
   Vitamin E is a fat-soluble antioxidant known to protect cell membranes from oxidative damage. It supports healthy skin, reduces inflammation, and works synergistically with vitamin C.
   Benefits:

• Protects collagen from degradation
• Improves skin hydration
• Slows signs of aging
• Reduces UV-induced skin damage

5. Hyaluronic Acid
   Hyaluronic acid is a naturally occurring substance in the body, known for its powerful ability to retain moisture. It is found in high concentrations in connective tissues such as skin, cartilage, and joints.
   Benefits:

• Hydrates the skin and reduces dryness
• Improves skin elasticity and firmness
• Supports joint lubrication and mobility
  Scientific Source:
  A study found that hyaluronic acid supplementation significantly improved skin hydration and elasticity in individuals with dry skin.
  https://pubmed.ncbi.nlm.nih.gov/26780128/

6. Copper
   Copper is an essential trace mineral that plays a key role in collagen formation and antioxidant protection. It supports the activity of enzymes that cross-link collagen fibers and enhance skin and bone health.
   Benefits:

• Promotes collagen synthesis
• Supports bone strength and structure
• Acts as a potent antioxidant
  Scientific Source:
  A clinical study indicated that copper supplementation contributes to improved skin elasticity and wound healing.
  https://pubmed.ncbi.nlm.nih.gov/25877389/

How Collagen 500+ Works in the Body

The bioactive peptides from Fortigel® are absorbed through the small intestine and enter the bloodstream. Studies show that these peptides accumulate in cartilage tissue, where they stimulate cells to produce new collagen and proteoglycans, improving the mechanical function of joints.

Simultaneously, vitamin C supports the enzymatic activity necessary for new collagen fiber assembly. Zinc and vitamin E reinforce the matrix by protecting collagen molecules from oxidative stress and inflammation, both of which degrade skin and connective tissues over time.

Who Can Benefit from Collagen 500+?

1. Adults Over 30

Once collagen production begins to decline, signs of aging become more apparent. Supplementing with Collagen 500+ can help maintain firmness in the skin, elasticity in the joints, and density in the bones.

2. Athletes or Physically Active People

Joints and cartilage are often under stress during intense physical activity. Fortigel® has been clinically shown to reduce joint discomfort in athletes and support recovery.

3. People with Joint Discomfort or Osteoarthritis

Studies indicate that collagen peptides may help reduce pain, improve mobility, and even slow cartilage degradation in individuals with osteoarthritis.

4. Individuals with Skin Concerns

For those noticing fine lines, sagging skin, or dryness, the combination of hydrolyzed collagen, vitamin C, E, and zinc offers powerful support from within.

What Makes Fortigel® Superior to Regular Collagen?

Many collagen supplements contain gelatin or generic collagen, which may be poorly absorbed. Fortigel® is enzymatically hydrolyzed into low-molecular-weight peptides, which are shown in studies to be absorbed quickly and deposited in skin and cartilage tissues.

One 2021 study confirmed that Fortigel® peptides remain detectable in blood plasma for up to 96 hours post-ingestion, demonstrating long-lasting systemic effects.

Dosage and Use

Collagen 500+ is most effective when taken daily for at least 8–12 weeks. This duration reflects clinical studies on Fortigel® and other supportive nutrients. For best results, take it with food—preferably at breakfast or lunch—to enhance the absorption of fat-soluble vitamins, like vitamin E.

Conclusion

Collagen 500+ by Cosmo Pharm® is more than just a beauty supplement—it’s a comprehensive approach to long-term joint, skin, and bone health. Powered by clinically studied Fortigel®, supported by essential cofactors like vitamin C, zinc, and vitamin E, this formula addresses the root causes of collagen loss and supports tissue repair and regeneration from the inside out.

Whether you’re an athlete, someone navigating the signs of aging, or simply interested in supporting your overall wellness, Collagen 500+ is a trustworthy, scientifically validated ally in your health routine.

Sources

https://pubmed.ncbi.nlm.nih.gov/18416885/
https://www.gelita.com/en/products/collagen-peptides/fortigel
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/
https://pubmed.ncbi.nlm.nih.gov/34905558/
https://pubmed.ncbi.nlm.nih.gov/31745908/
https://pubmed.ncbi.nlm.nih.gov/33669621/
https://pubmed.ncbi.nlm.nih.gov/26780128/
https://pubmed.ncbi.nlm.nih.gov/25877389/