Respirox Pulmonary Detox: A Scientific Review of Its Herbal Composition and Respiratory Benefits

Respiratory health is a cornerstone of overall well-being. In our increasingly polluted environment, with exposure to allergens, smoke, and viral infections, maintaining lung function is essential. Respirox Pulmonary Detox, a dietary supplement from Cosmopharm, contains a blend of natural, plant-based extracts that aim to support the respiratory system. Its ingredients are selected for their scientifically-supported benefits, including their anti-inflammatory, expectorant, antimicrobial, and bronchodilatory properties.

This article provides a thorough scientific overview of the ingredients in Respirox, outlining their mechanisms of action, potential benefits, and the research supporting their use in respiratory health.

 Composition of Respirox Pulmonary Detox

Respirox Pulmonary Detox is formulated with a combination of standardized plant extracts. Each ingredient has been carefully chosen based on its proven therapeutic benefits for the respiratory system.

1. Mullein Leaf (Verbascum thapsus)

Amount per capsule: 75 mg (4:1 extract from leaves)

Mullein has been used for centuries in traditional medicine for respiratory issues. It has strong expectorant properties that help the body expel mucus, easing coughing and clearing airways. Mullein contains saponins, flavonoids, and phenolic compounds, all of which contribute to its anti-inflammatory and soothing effects on the lungs.

Studies have shown that mullein extract can alleviate symptoms of asthma, bronchitis, and other inflammatory airway diseases. In vitro studies suggest that mullein’s bioactive compounds help reduce inflammatory cytokines and promote the thinning of mucus, making it easier to expel. (PubMed).
Mullein is widely known for its expectorant and anti-inflammatory properties. These effects are primarily due to the presence of saponins and flavonoids. Saponins help by stimulating the production of thinner mucus, making it easier to expel thick, sticky mucus from the lungs. This expectorant action can be particularly beneficial for conditions such as bronchitis or chronic obstructive pulmonary disease (COPD).

The flavonoids in mullein have potent anti-inflammatory and antioxidant effects, reducing the inflammation in the respiratory tissues and protecting the cells from oxidative stress. This combination of actions contributes to its effectiveness in soothing irritated airways and promoting better lung function.

2. Lungwort (Pulmonaria officinalis)

Amount per capsule: 75 mg (4:1 extract from aerial parts)

Lungwort, named after its traditional use for respiratory ailments, contains mucilaginous compounds that help soothe the mucosal lining of the respiratory tract. It is believed to provide relief for coughing and hoarseness, as well as support lung detoxification.

Although lungwort’s use in modern medicine is limited, animal studies have shown its potential to calm inflammation and reduce respiratory tract irritation. The mucilaginous compounds present are thought to coat the respiratory tissues, reducing irritation caused by conditions such as coughs and bronchitis. More research is needed to fully understand its therapeutic potential. (PubMed).
Lungwort’s key mechanism of action is its mucilaginous properties, which create a protective layer over the mucous membranes of the respiratory tract. This layer helps to soothe irritation caused by coughing, dryness, or inflammation. The mucilage also acts as a mild expectorant, facilitating the clearance of mucus from the respiratory passages.

Lungwort contains flavonoids and tannins, which contribute to its antioxidant and anti-inflammatory effects. These bioactive compounds help to reduce inflammation in the lungs and protect lung tissues from damage caused by free radicals. Lungwort’s combined actions of soothing and protecting the respiratory lining make it useful for alleviating symptoms of upper respiratory infections and chronic cough.

3. Plantain Leaf (Plantago lanceolata)

Amount per capsule: 50 mg (4:1 extract from leaves)

Plantain has been used for centuries to treat a variety of lung conditions, from bronchitis to asthma. It has known anti-inflammatory, antimicrobial, and bronchodilatory effects, making it beneficial in the treatment of respiratory conditions. Its active compounds, such as aucubin and catalpol, help modulate the inflammatory processes in the lungs.

A clinical study found that plantain leaf extract significantly improved symptoms in patients with chronic respiratory conditions by reducing inflammation in the airways and increasing lung function. It is also known to alleviate coughing and promote mucus clearance. (PubMed).
Plantain is known for its anti-inflammatory, antimicrobial, and expectorant properties. It contains active compounds like aucubin and catalpol, which help reduce inflammation in the respiratory airways and support the immune response. Plantain’s anti-inflammatory action targets the cytokines that contribute to airway constriction, making it easier to breathe.

Additionally, plantain’s expectorant effects facilitate the clearing of mucus from the respiratory system, easing congestion and promoting better airflow. Studies suggest that plantain may also help soothe irritated throat tissues, which makes it particularly effective for managing symptoms of acute respiratory conditions like the common cold or bronchitis.

4. Licorice Root (Glycyrrhiza glabra)

Amount per capsule: 50 mg (4:1 extract from root)

Licorice root is widely used for its soothing effects on the mucous membranes. It has anti-inflammatory and expectorant properties, making it useful in the treatment of coughs, sore throats, and respiratory infections. Glycyrrhizin, the active compound in licorice, can also enhance the effects of other medications used in asthma and chronic obstructive pulmonary disease (COPD).

Research shows that licorice root can improve the effectiveness of bronchodilators in asthma treatment by helping to relax the smooth muscles of the airways. However, it must be used cautiously as long-term use can lead to side effects, such as hypertension and potassium imbalances. (VeryWellHealth).
Licorice root acts as a powerful anti-inflammatory and immunomodulatory agent. The active compound glycyrrhizin is responsible for many of licorice’s therapeutic effects. Glycyrrhizin helps reduce inflammation by inhibiting the production of pro-inflammatory cytokines. It also enhances the function of immune cells, which supports the body’s ability to combat respiratory infections.

Licorice root also helps soothe the mucous membranes of the respiratory tract, promoting a reduction in coughing and throat irritation. Additionally, it can act as a mild expectorant, aiding in the expulsion of mucus from the lungs.

5. Elderberry Fruit (Sambucus nigra)

Amount per capsule: 50 mg (4:1 extract from fruit)

Elderberry is well-known for its immune-boosting properties. It is commonly used to treat colds and flu and can reduce the severity and duration of upper respiratory infections. Elderberry extract is rich in flavonoids, which have potent antiviral and antioxidant effects, helping to reduce inflammation and support overall lung health.

A systematic review concluded that elderberry supplementation can reduce the duration and severity of cold symptoms, particularly when taken at the onset of illness. Additionally, elderberry’s antiviral properties make it a promising natural remedy for respiratory infections. (PubMed).
Elderberry is well-known for its antiviral properties, particularly in the treatment of viral respiratory infections like the flu and common cold. The flavonoids in elderberry, especially anthocyanins, possess potent antioxidant properties that reduce oxidative stress in the body, which is often associated with inflammation in the lungs.

Elderberry works by inhibiting the replication of viruses, especially influenza, by blocking the viral attachment to host cells in the respiratory tract. This action helps reduce the severity and duration of upper respiratory infections and prevents secondary complications like bacterial pneumonia.

6. Thyme Aerial Parts (Thymus vulgaris)

Amount per capsule: 50 mg (4:1 extract from aerial parts)

Thyme is well-regarded for its ability to relieve symptoms of respiratory infections, including cough and congestion. Its active compounds, such as thymol and carvacrol, exhibit strong antimicrobial and anti-inflammatory effects. Thyme is also known to relax the muscles of the respiratory tract, making it easier to breathe.

Numerous studies have demonstrated thyme’s antimicrobial activity, particularly in the context of respiratory infections. Additionally, thyme’s ability to relax smooth muscle and reduce inflammation has been supported by clinical trials, showing improvements in symptoms of asthma and bronchitis. (PubMed).
Thyme contains two key bioactive compounds: thymol and carvacrol. These compounds have strong antimicrobial, anti-inflammatory, and bronchodilatory properties. Thyme works by relaxing the smooth muscle of the bronchial airways, which helps relieve symptoms of bronchospasm and tightness in conditions like asthma or chronic bronchitis.

Thyme also has expectorant effects, helping to thin mucus in the lungs and make it easier to expel. Its antimicrobial properties are beneficial in combating respiratory infections by inhibiting the growth of bacteria, fungi, and viruses that can cause lung-related illnesses.

7. Ginger Rhizome (Zingiber officinalis)

Amount per capsule: 50 mg (Standardized extract with min. 5% gingerols)

Ginger is a well-known anti-inflammatory and antioxidant herb with a wide range of medicinal properties. In the context of respiratory health, ginger can help reduce inflammation in the airways and improve circulation, which aids in the removal of toxins from the lungs.

Ginger’s active compounds, particularly gingerols, have been shown to reduce airway inflammation and improve lung function. Studies have suggested that ginger may be beneficial in the treatment of asthma, chronic bronchitis, and other inflammatory lung diseases. (PubMed).
Ginger is widely known for its anti-inflammatory, antioxidant, and thermogenic properties. The active compounds in ginger, gingerols, inhibit the activity of inflammatory mediators in the body, such as cyclooxygenase (COX) enzymes. This reduces inflammation in the airways and helps alleviate symptoms of asthma and other chronic respiratory conditions.

Additionally, ginger helps relax the smooth muscle of the respiratory tract, which makes it easier to breathe. It also promotes better circulation and supports the elimination of toxins from the body, potentially improving overall lung health and enhancing the immune system’s ability to fight respiratory infections.

8. Black Radish (Raphanus sativus)

Amount per capsule: 50 mg (10:1 extract from root)

Black radish has long been used for its detoxifying and respiratory benefits. It is known to stimulate bile production, which aids in detoxifying the liver and improving overall metabolism. When it comes to respiratory health, black radish helps break down and expel mucus from the lungs, making it easier to breathe.

Research has demonstrated the effectiveness of black radish in supporting lung health, particularly in clearing mucus and relieving congestion. Animal studies have shown that black radish stimulates the production of bile, promoting the elimination of toxins from the body, which in turn supports the lungs. Furthermore, its antimicrobial properties help reduce the risk of infections in the respiratory tract. (PubMed).
Black radish is traditionally used as a detoxifying agent, particularly for the liver and lungs. The active compounds in black radish stimulate the production of bile, which helps in the digestion and elimination of toxins. In the lungs, black radish acts as an expectorant, aiding in the clearance of mucus from the airways.

Additionally, black radish has antimicrobial properties, which may help reduce the risk of infections in the respiratory tract, especially in individuals with weakened immune systems or chronic lung conditions.

9. Black Cumin Seed (Nigella sativa)

Amount per capsule: 25 mg (4:1 extract from seeds)

Black cumin seeds are highly regarded for their broad spectrum of health benefits, especially their anti-inflammatory, antioxidant, and immune-boosting properties. In respiratory health, black cumin seed supports the lungs by reducing inflammation and easing the symptoms of conditions like asthma, bronchitis, and allergies.

Several studies have supported the use of black cumin seed oil for asthma treatment, showing its ability to reduce airway inflammation and improve lung function. The active compound thymoquinone has been shown to inhibit the production of inflammatory cytokines, which helps to reduce airway constriction. Black cumin is also thought to enhance the body’s immune response, making it a valuable herb for respiratory support. (PubMed, NIH).
Black cumin seed contains the active compound thymoquinone, which has significant anti-inflammatory, antioxidant, and immunomodulatory effects. Thymoquinone has been shown to inhibit inflammatory pathways, such as the NF-kB and COX-2 pathways, reducing inflammation in the respiratory tract.

Black cumin also has bronchodilatory properties, helping to relax the muscles in the airways, making it easier to breathe. Its immune-boosting effects further contribute to the body’s ability to fight off respiratory infections and maintain lung health.

10. Wormwood (Artemisia absinthium)

Amount per capsule: 25 mg (4:1 extract from aerial parts)

Wormwood is a bitter herb that has been traditionally used for a range of health conditions, including digestive issues and respiratory ailments. It helps support lung health by reducing inflammation and alleviating symptoms of respiratory infections. Additionally, wormwood has mild antimicrobial properties that can aid in the prevention of infections in the respiratory tract.

Wormwood contains artemisinin and other sesquiterpene lactones that have demonstrated anti-inflammatory and antimicrobial effects in laboratory studies. These compounds may help relieve symptoms of asthma, bronchitis, and other respiratory diseases. Wormwood has also shown potential in modulating immune function, further supporting lung health. (PubMed).
Wormwood contains artemisinin and other sesquiterpene lactones, which have strong anti-inflammatory and antimicrobial properties. Wormwood works by inhibiting the growth of pathogens in the respiratory system, including bacteria and fungi. It also promotes the clearance of mucus, making it easier to expel respiratory secretions.

Wormwood’s antioxidant properties help protect the lung tissues from oxidative damage and support the immune system in defending against respiratory infections.

11. Marshmallow Root (Althaea officinalis)

Amount per capsule: 25 mg (4:1 extract from root)

Marshmallow root is known for its mucilaginous properties, which allow it to form a soothing layer over mucous membranes in the respiratory tract. This helps reduce irritation and inflammation caused by coughing, sore throat, or other respiratory conditions. Marshmallow root also supports the elimination of mucus, making it easier to breathe.

The mucilage in marshmallow root helps to coat and protect the mucous membranes in the throat and lungs, easing irritation and reducing coughing. Clinical studies have shown that marshmallow root can be effective in alleviating symptoms of chronic cough, bronchitis, and other respiratory conditions. Its gentle expectorant properties also promote the expulsion of mucus from the lungs. (PubMed, NIH).
Marshmallow root contains mucilage, a gel-like substance that coats the mucous membranes of the respiratory tract, soothing irritation and reducing inflammation. This makes marshmallow root effective for relieving dry coughs and soothing irritated throats.

Additionally, marshmallow root has mild expectorant properties, helping to thin mucus and support the expulsion of excess secretions. It also helps protect against damage caused by inflammation in the respiratory tissues.

The combination of these herbal extracts in Respirox Pulmonary Detox works synergistically to provide a multi-faceted approach to respiratory health. Whether by reducing inflammation, promoting mucus clearance, boosting the immune system, or inhibiting pathogens, each ingredient contributes to improving respiratory function and overall lung health. This complex interplay of mechanisms makes Respirox a potent ally in managing both acute and chronic respiratory conditions.

12.Black Pepper Fruit (Piper nigrum)
Amount per capsule: 5 mg (Standardized extract from fruit with min. 95% piperine)

Black pepper, commonly used as a culinary spice, has also gained recognition in phytotherapy due to its potent bioactive compound—piperine. In the context of respiratory health, piperine serves a crucial role in enhancing the bioavailability of other herbal ingredients, allowing for better absorption and more effective results.

Piperine has been shown to stimulate the secretion of digestive enzymes, which supports nutrient assimilation. More importantly for respiratory detoxification, it acts on metabolic enzymes such as CYP450, increasing the systemic absorption of antioxidants and anti-inflammatory compounds found in other plant extracts. This synergistic effect can significantly boost the overall efficacy of the formula.

Scientific studies have confirmed that piperine enhances the bioavailability of numerous compounds, including curcumin, resveratrol, and various flavonoids—many of which are present in other herbs in this formula. Additionally, piperine itself exhibits anti-inflammatory, bronchodilatory, and antioxidant properties, helping reduce airway inflammation and oxidative stress in lung tissues. (PubMed).

Piperine also plays a direct role in modulating immune response and suppressing pro-inflammatory cytokines like IL-6 and TNF-α. This can be especially beneficial in respiratory infections and chronic inflammatory lung conditions such as asthma and COPD. Furthermore, it has mild thermogenic effects, which may assist in stimulating circulation and detoxification processes within the lungs.

Due to its multiple mechanisms of action—bioenhancement, anti-inflammatory modulation, and mild bronchodilation—black pepper extract is a key supportive component of the Respirox Pulmonary Detox formula, ensuring that the therapeutic potential of all other ingredients is fully realized.

Potential Benefits of Respirox Pulmonary Detox

Respirox Pulmonary Detox is designed to address a wide range of respiratory issues by targeting both acute and chronic conditions. The blend of plant extracts in Respirox works synergistically to provide the following potential benefits:

1. Support for Respiratory Health

The active ingredients in Respirox, such as mullein, plantain, and thyme, are known for their ability to support respiratory function by reducing inflammation and promoting mucus clearance. These effects may help individuals suffering from chronic conditions like asthma, bronchitis, or chronic obstructive pulmonary disease (COPD).

Studies have found that compounds from these plants can help reduce airway inflammation, improve lung function, and decrease symptoms like wheezing, coughing, and shortness of breath. (PubMed).

2. Immunomodulation and Antiviral Effects

Elderberry and licorice root contribute to the supplement’s immune-boosting properties. Elderberry is especially effective in reducing the severity of viral infections, such as colds and flu, while licorice root supports the immune system’s ability to fight off respiratory pathogens.

Elderberry has shown significant antiviral effects, helping to reduce the duration and severity of upper respiratory infections, especially when taken early. (PubMed). Licorice root also enhances the action of immune cells and reduces inflammation in respiratory tissues, helping the body combat infections. (PubMed).

3. Antioxidant and Anti-inflammatory Effects

Ginger and thyme are rich in antioxidants and anti-inflammatory compounds, which help protect the lungs from oxidative stress and reduce the inflammation that often accompanies respiratory conditions.

Research on ginger has demonstrated its ability to reduce oxidative stress and inflammation in the lungs, which is particularly beneficial for conditions like asthma and chronic bronchitis. (PubMed). Likewise, thyme’s active compounds (e.g., thymol and carvacrol) are known to reduce inflammatory markers, which may improve lung health and function. (PubMed).

4. Respiratory Detoxification

Black radish and licorice root support the body’s natural detoxification processes, specifically targeting the respiratory system. These herbs promote the elimination of toxins from the body, potentially improving lung health by reducing the toxic load in the airways.

While scientific evidence is still emerging, black radish has long been used as a natural remedy for detoxifying the liver and lungs, particularly in the case of smokers or those with chronic lung conditions. Licorice root also supports detoxification by promoting the flow of mucus and assisting in the expulsion of waste from the lungs. (PubMed).

Dosage and Administration

Respirox Pulmonary Detox should be taken as directed by the manufacturer or a healthcare professional. The standard dosage is:

• Recommended Dosage: Take 1 capsule twice daily with meals and a glass of water, or as recommended by a healthcare provider.
• Duration of Use: One box containing 30 capsules lasts for 15 days.
• It is recommended to follow a minimum 3-month regimen, followed by a 1-month break. After this period, administration can be resumed if necessary.

It is important to note that Respirox is a dietary supplement and should be used in conjunction with a healthy diet and lifestyle for maximum benefit. The effectiveness may vary depending on individual health conditions, and it is recommended to consult a healthcare professional before beginning any supplement regimen.

Safety and Quality Assurance

Cosmopharm’s Respirox Pulmonary Detox is manufactured in compliance with strict Good Manufacturing Practices (GMP) to ensure the highest standards of safety and quality. The ingredients used are carefully sourced, and each batch undergoes rigorous testing to confirm their potency, purity, and safety.

Safety Considerations:

• Consultation with Healthcare Providers: Respirox is generally considered safe for most individuals when taken as directed. However, pregnant or breastfeeding women, individuals with underlying health conditions, or those taking prescription medications should consult a healthcare provider before using this supplement.
• Allergy Information: Those allergic to any of the plant components, such as ginger, licorice, or elderberry, should avoid using this product.
• Side Effects: Although rare, some individuals may experience mild digestive discomfort (e.g., bloating or nausea) when using herbal supplements. If any adverse effects occur, discontinue use and consult a healthcare provider immediately.

Conclusion

Respirox Pulmonary Detox offers a potent blend of natural herbs, each scientifically supported for its role in promoting respiratory health. The synergistic effects of ingredients like mullein, thyme, elderberry, and licorice root may help support individuals with both chronic and acute respiratory issues by reducing inflammation, promoting mucus clearance, and enhancing immune function.

While Respirox provides numerous benefits, it is essential to remember that dietary supplements should complement, not replace, professional medical treatment. Individuals with chronic respiratory conditions should consult a healthcare provider for a comprehensive management plan.

Sources

PubMed – Verbascum thapsus

PubMed – Pulmonaria officinalis

PubMed – Plantago lanceolata

PubMed – Glycyrrhiza glabra

PubMed – Sambucus nigra

PubMed – Thymus vulgaris

PubMed – Zingiber officinale

PubMed – Raphanus sativus

PubMed – Nigella sativa

PubMed – Artemisia absinthium

PubMed – Althaea officinalis